• Significant correlation exists between radiological parameters such as volumetric and ADC values and major genomic profiles such as IDH mutation and ATRX loss status • Radiological parameters such as the ADC value were feasible predictors of glioblastoma patients' prognosis • Imaging features can predict major genomic profiles of the tumours and the prognosis of glioblastoma patients.
• Significant correlation exists between radiological parameters such as volumetric and ADC values and major genomic profiles such as IDH mutation and ATRX loss status • Radiological parameters such as the ADC value were feasible predictors of glioblastoma patients' prognosis • Imaging features can predict major genomic profiles of the tumours and the prognosis of glioblastoma patients.
• Significant correlation exists between radiological parameters such as volumetric and ADC values and major genomic profiles such as IDH mutation and ATRX loss status • Radiological parameters such as the ADC value were feasible predictors of glioblastoma patients' prognosis • Imaging features can predict major genomic profiles of the tumours and the prognosis of glioblastoma patients.
• Significant correlation exists between radiological parameters such as volumetric and ADC values and major genomic profiles such as IDH mutation and ATRX loss status • Radiological parameters such as the ADC value were feasible predictors of glioblastoma patients' prognosis • Imaging features can predict major genomic profiles of the tumours and the prognosis of glioblastoma patients.
• Significant correlation exists between radiological parameters such as volumetric and ADC values and major genomic profiles such as IDH mutation and ATRX loss status • Radiological parameters such as the ADC value were feasible predictors of glioblastoma patients' prognosis • Imaging features can predict major genomic profiles of the tumours and the prognosis of glioblastoma patients.
ΔEGFR cooperated with STAT5b to regulate the Bcl-XL promoter and knockdown of STAT5b suppressed anchorage independent growth, reduced the levels of Bcl-XL and sensitized glioblastoma cells to cisplatin.
[Corrigendum] LRIG2 promotes the proliferation and cell cycle progression of glioblastoma cells in vitro and in vivo through enhancing PDGFRβ signaling.
[<sup>177</sup>Lu]DOTA-[Thi⁸,Met(O₂)<sup>11</sup>]SP(1⁻11), [<sup>177</sup>Lu]DOTA-SP(4⁻11) and [<sup>177</sup>Lu]DOTA-[Thi⁸,Met(O₂)<sup>11</sup>]SP(5⁻11) radiobioconjugates bound specifically to NK-1 receptors expressed on glioblastoma cells with affinity in the nanomolar range.
[<sup>177</sup>Lu]DOTA-[Thi⁸,Met(O₂)<sup>11</sup>]SP(1⁻11), [<sup>177</sup>Lu]DOTA-SP(4⁻11) and [<sup>177</sup>Lu]DOTA-[Thi⁸,Met(O₂)<sup>11</sup>]SP(5⁻11) radiobioconjugates bound specifically to NK-1 receptors expressed on glioblastoma cells with affinity in the nanomolar range.
[<sup>177</sup>Lu]DOTA-[Thi⁸,Met(O₂)<sup>11</sup>]SP(1⁻11), [<sup>177</sup>Lu]DOTA-SP(4⁻11) and [<sup>177</sup>Lu]DOTA-[Thi⁸,Met(O₂)<sup>11</sup>]SP(5⁻11) radiobioconjugates bound specifically to NK-1 receptors expressed on glioblastoma cells with affinity in the nanomolar range.
[<sup>111</sup>In]In-NODAGA-Z<sub>VEGFR2</sub>-Bp<sub>2</sub> appears to be a promising probe for in vivo noninvasive visualization of tumor angiogenesis in glioblastoma.
YWHAG was able to accelerate the phosphorylation of MDM4 and lead to the degradation of P53, which provides a potential mechanism for the tumor-promoting role of miR-217 in glioblastoma cells.
YWHAG was able to accelerate the phosphorylation of MDM4 and lead to the degradation of P53, which provides a potential mechanism for the tumor-promoting role of miR-217 in glioblastoma cells.